Up to 40% have unknown causes. This can be due to a PFO in 60% of cases. We now refer to these cases as “PFO-related stroke".

Our studies show that for some people, a cardiac condition, known as a PFO, is a major contributing factor to migraine with aura.

The 'gold standard' screening for a 'hole in the heart' misses up to 15% of PFOs. Instead we use a tool that's safer, faster & more accurate